Effects of tranexamic acid combined with uterine stent balloon compression on postpartum hemorrhage of placenta previa
Objective To explore the therapeutic effect of tranexamic acid combined with uterine stent balloon compression on postpartum hemorrhage of placenta previa.Methods According to different treatment plans,60 patients with postpartum hemorrhage of placenta previa were admitted to Xinyang Vocational and Technical College Affiliated Hospital from January 2021 to January 2023 were divided into two groups,with 30 cases in each group.The control group were treated with uterine stent balloon compression,and the combined group were treated with tranexamic acid on the basis of the control group.The treatment efficacy,surgical indicators,uterine artery hemodynamic indicators,uterine artery pulsatile index(PI),resistance index(RI),coagulation function indicators,fibrinogen(FIB),prothrombin time(PT),activated partial prothrombin time(APTT),D-dimer(D-D),complications and adverse reactions were compared between the two groups.Results The total effective rate of the combined group was 96.67%,which was higher than that of the control group(73.33%),the difference was statistically significant(P<0.05).After treatment,the blood loss 2 h and 24 h postpartum in the combination group was less than that in the control group,the hemostatic time and hospital stay were shorter,and the levels of PI,RI,FIB and D-D were higher than those in the control group(P<0.05).There was no significant difference in the incidence of PT,APTT and adverse reactions between the two groups(P>0.05),and the incidence of complications in the combined group was lower than that in the control group(P<0.05).Conclusion Tranexamic acid combined with uterine stent balloon compression in the treatment of placental previa postpartum hemorrhage can effectively improve uterine artery hemodynamics,promote coagulation function stability,and have better hemostatic and therapeutic effects.
tranexamic acidballoon compressionplacental previapostpartum hemorrhagecoagulation function
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