摘要
目的 研究某县农村人群糖化血红蛋白(HbA1c)水平及其影响因素.方法 对某县人群进行横断面调查,收集一般情况及流行病学资料,检测血脂、糖化血红蛋白等指标.采用检验、方差分析和多因素线性回归模型进行分析.结果 有2 949 名参与者符合条件并纳入分析,HbA1c平均水平为5.794%.将单因素中有意义的变量[年龄、低密度脂蛋白(LDL-c)、甘油三酯(TG)、腰围(WC)、尿素、收缩压(SBP)等]纳入多因素分析.多因素线性回归分析结果显示,年龄、LDL-C、TG、SBP、WC、尿素与HbA1c水平呈显著正相关,差异有统计学意义(P<0.05).结论 年龄、TG、LDL-C、SBP、WC、尿素与糖化血红蛋白水平呈正相关,需要开展有针对性措施,继而进行积极预防,最大程度提高人群的生活质量.
Abstract
Objective To study the level of glycosylated hemoglobin(HbA1c)and its influencing factors in rural population of a county.Methods A cross-sectional survey was conducted to collect the general situation and epidemiological data in one county.Blood lipid,HbA1c and other indicators were detected.T-test,analysis of variance and multiple Linear regression model were used for analysis.Results There were 2949 participants being eligible for inclusion in the analysis.The average level of HbA1c was 5.794%.Variables of univariate significance(age,low-density lipoprotein,triglycerides,waist circumference,urea,systolic blood pressure etc.)were included in the multivariate analysis.Multivariate linear regression analysis showed that age,low-density(LDL-C),triglyceride(TG),systolic blood pressure(SBP),waist circumference(WC),urea were positively correlated with HbA1c levels,the difference was statistically significant(P<0.05).Conclusion Age,TG,LDL-C,SBP,WC,urea and glycosylated hemoglobin levels are positively correlated,and targeted measures should be taken to actively prevent and maximize the quality of life of the population.
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