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小儿支原体大叶性肺炎的诊断模型建立

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目的 通过Logistics回归建立肺炎支原体(MP)患儿并发大叶性肺炎的列线图诊断模型.方法 选取2018 年6 月至2023 年6 月住院的239 例MP 患儿,依据临床资料分为常规肺炎组(78 例)和大叶性肺炎组(161 例).利用Lasso回归模型筛选大叶性肺炎的相关指标,并应用Logistics回归构建列线图诊断模型.结果 单因素分析发现年龄、咳嗽史、白细胞计数(WBC)、中性粒细胞计数(NEU)、血小板(PLT)、乳酸脱氢酶(LDH)与大叶性肺炎相关.Lasso回归筛选出年龄、咳嗽史、WBC、NEU、CRP、LDH和痰栓与大叶性肺炎强相关.Logistics回归分析表明年龄、咳嗽史、WBC、LDH和痰栓是大叶性肺炎患者的独立诊断因素.列线图诊断模型在区分小儿MP与大叶性肺炎方面展现出良好的实用性.结论 采用Lasso和Logistics回归构建MP 并发大叶性肺炎的列线图诊断模型的诊断效能高,模型C指数0.803,对MP患儿并发大叶性肺炎的诊断与治疗有重要意义.
Establishment of a diagnosis model for pediatric mycoplasma pneumonia and lobar pneumonia
Objective To establish a diagnostic model for children with mycoplasma pneumoniae(MP)complicated with lobar pneumonia by Logistics regression.Methods The clinical data of 239 children hospitalized with Mycoplasma pneumoniae between June 2018 and June 2023 were retrospectively analyzed and divided into the conventional pneumonia group(78 cases)and the lobar pneumonia group(161 cases).Lasso regression model was utilized to screen the relevant features of lobar pneumonia,and Logistics regression was applied to construct a diagnostic prediction model.Results Univariate analysis revealed that age,cough history,white blood cells count(WBC),neutrophil count(NEU),platelets(PLT),lactate dehydrogenase(LDH)were associated with lobar pneumonia.The age,cough history,WBC,NEU,CRP,LDH,and bolus screened by lasso regression were strongly associated with lobar pneumonia.Logistics regression analysis showed that age,cough history,WBC,LDH,and bolus were independent diagnostic factors in patients with lobar pneumonia.The Nomogram model showed good discrimination and clinical utility in distinguishing pediatric MP from lobar pneumonia.differentiation and clinical utility.Conclusion Lasso and Logistic regression are studied to construct a column-line graph model,and age,cough history,WBC,LDH,and talk embolism are found to be independent diagnostic factors for MP complicated with lobar pneumonia.And the model has a C-index of 0.803,which is highly accurate and helps clinical decision-making.

mycoplasma pneumoniaechildrenpneumonialobar pneumoniadiagnostic models

石家云、刘小峰、梁麟龙、谢齐放

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南华大学衡阳医学院附属长沙中心医院儿科,长沙 410004

肺炎支原体 儿童 肺炎 大叶性肺炎 诊断模型

湖南省自然科学基金科卫联合项目

2019JJ80108

2024

华夏医学
桂林医学院

华夏医学

影响因子:0.569
ISSN:1008-2409
年,卷(期):2024.37(2)
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