Effect analysis of continuous blood purification assisted bytolvaptan in the treatment of acute left heart failure
Objective To observing the clinical effect of combined therapy with blood purification to treat acute left heart failure.Methods 100 patients with acute left heart failure were selected and randomly divided into the combination group and conventional group using a number table method,with 50 cases in each group.The conventional group were received continuous blood purification treatment,while the combined group were received adjuvant treatment with tolvaptan.The changes in electrolytes and cardiac function before and after treatment,as well as the clinical indicators and prognosis of the two groups of patients were compared.Results After treatment,the combined group had lower levels of NT-ProBNP and higher blood sodium levels than that in the conventional group,and difference was statistically signifcant(P<0.05).In the combined group,LVEF was higher than that in the conventional group,while LVDD and sPAP were lower than that in the conventional group(P<0.05).The intubation time,ICU stay time,respiratory support assistance rate,hospitalization time,and incidence of adverse events in the control group were lower than those in the conventional group(P<0.05).Conclusion The treatment of acute left heart failure with continuous blood purification assisted by tolvaptan can effectively improve patient electrolyte levels and promote cardiac function recovery,which has positive significance in accelerating patient recovery process and reducing the risk of adverse events.
tolvaptancontinuous blood purificationacute left heart failure
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