Effects of sufentanil on off-pump coronary artery bypass
Objective To observe the effects of different doses of sufentanil on off-pump coronary artery bypass(OPCAB).Methods 115 patients who underwent OPCAB surgery were divided into two groups using a number table method,with 57 patients in each group.The conventional group were received conventional dose sufentanil as an adjuvant for OPCAB surgery,while the experimental group were received low dose sufentanil as an adjuvant for OPCAB surgery.The changes in perioperative physical signs,anesthesia analgesia,sedation effects,awakening status,and occurrence of anesthesia related adverse reactions after awakening were compared between the two groups patients.Results Under different anesthesia regimens,there were no statistically significant differences between the experimental group and the conventional group in terms of heart rate(HR),mean arterial pressure(MAP)at T0 and T2,VAS and RASS scores after awakening,and intraoperative awareness rate(P>0.05);the HR and MAP of the experimental group at T1 and T3 were higher than those of the conventional group,while the awakening time and CSICU stay time in experimental group were lower than those of the conventional group(P<0.05);the difference in the incidence of anesthesia related adverse reactions between the two groups was statistically significant(P<0.05).Conclusion Low dose sufentanil assisted OPCAB anesthesia can effectively maintain the stability of patients' basic signs during the perioperative period,with good analgesic and sedative effects,low risk of adverse reactions,and high safety.
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