清肺养阴汤联合无创通气对慢性阻塞性肺疾病的治疗效果
Effects of Qingfei-Yangyin decoction combined with non-invasive ventilation in the treatment of chronic obstructive pulmonary disease
李晓娜 1侯帅辉 2王才利1
作者信息
- 1. 偃师人民医院 中医科,偃师 471900
- 2. 偃师人民医院 呼吸科,偃师 471900
- 折叠
摘要
目的 探究清肺养阴汤联合无创通气治疗慢性阻塞性肺疾病(COPD)的效果及其对肺顺应性、氧合功能的影响.方法 选取 2021 年 6 月至 2023 年 6 月偃师人民医院接诊的 130 例COPD患者,按随机数字表法分为观察组(n=65 例)和对照组(n=65 例),对照组给予无创通气治疗,观察组给予无创通气联合清肺养阴汤治疗,两组均治疗2 周.分析两组治疗效果,中医证候积分,肺功能指标第1 秒用力呼气容积(FEV1)、最大呼气流量(MEF)、FEV1占预计值的百分比(FEV1%pred)和肺活量(FVC),氧合功能指标氧合指数(PaO2/FiO2)、动脉血二氧化碳分压(PaCO2)和动脉血氧分压(PaO2)及肺顺应性.结果 观察组治疗总有效率为 95.38%,高于对照组 83.08%,差异有统计学意义(P<0.05);治疗2 周后,观察组中医证候积分低于对照组,FVC、MEF、FEV1%pred、FEV1高于对照组(P<0.05);观察组PaO2、PaO2/FiO2高于对照组,PaCO2、肺顺应性低于对照组(P<0.05).结论 清肺养阴汤联合无创通气治疗COPD能促进肺功能、肺顺应性及氧合功能改善,减轻临床症状,提高治疗效果.
Abstract
Objective To explore the effects of Qingfei-Yangyin decoction combined with non-invasive ventilation on chronic obstructive pulmonary disease(COPD)and its influence on lung compliance and oxygenation function.Methods 130 patients with COPD in Yanshi People's Hospital from June 2021 to June 2023 were selected and randomly divided into observation group(n=65)and control group(n=65).The control group was treated with non-invasive ventilation,and the observation group was treated with Qingfei-Yangyin decoction combined with non-invasive ventilation.Both groups were treated for two weeks.The therapeutic effects of two groups,including TCM syndrome score,forced expiratory volume in the first second(FEV1),maximal expiratory flow(MEF),percentage of FEV1 in predicted value(FEV1%pred),fored vital capacity(FVC),oxygenation index(PaO2/FiO2),arterial partial pressure of carbon dioxide(PaCO2),arterial partial pressure of oxygen(PaO2)and lung compliance were analyzed.Results The total effective rate of the observation group treatment was 95.38%in the observation group,which was higher than 83.08%in the control group(P<0.05).Compared with the control group,the TCM syndrome score of the observation group was lower after 2 weeks of treatment(P<0.05).After 2 weeks of treatment,FVC,MEF,FEV1%pred and FEV1 in the observation group were higher than those in the control group(P<0.05)PaO2 and PaO2/FiO2 in the observation group were higher,and PaCO2 and lung compliance were lower(P<0.05).Conclusion Qingfei-Yangyin decoction combined with non-invasive ventilation in the treatment of COPD patients can significantly enhance the curative effect,improve lung function,lung compliance and oxygenation function,and reduce clinical symptoms.
关键词
慢性阻塞性肺疾病/清肺养阴汤/无创通气/氧合功能/肺顺应性Key words
chronic obstructive pulmonary disease/Qingfei-yangyin decoction/non-invasive ventilation/oxygenation function/lung compliance引用本文复制引用
基金项目
河南省医学科技攻关计划联合共建项目(LHGJ20221015)
出版年
2024
NETL
NSTL
万方数据