Predictive value of combined detection of five coagulation parameters and thromboelastography for the prognosis of ACI
Objective To explore the predictive value of combined detection of five coagulation parameters and thromboelastography for the prognosis of acute cerebral infarction(ACI).Methods 216 ACI patients were selected,the five coagulation parameters(PT,DD,TT,APTT,FIB)were measured,and the correlation between thromboelastography indicators(K,R,MA,angle α,CI)and the severity of ACI were analyzed.The predictive value of combined detection of coagulation and thromboelastography indicators at admission for the prognosis of ACI patients were analyzed.Results At admission,PT,TT,R,and K were compared,with mild>moderate>severe,and the difference was statistically significant(P<0.05).Comparison of DD,FIB,angle a,and MA:mild<moderate<severe(P<0.05).At admission,R and K were negatively correlated with the severity of ACI,DD,FIB,and positively correlated with PT and TT.Angle α and MA were positively correlated with the severity of ACI,DD,FIB,and negatively correlated with PT and TT(P<0.05).The combined detection of thromboelastography indicators R,K,angle α,MA,CI,and coagulation indicators PT,DD,TT,and FIB at admission predicted a poor prognosis for ACI patients with an AUC of 0.946,which was greater than the individual detection of the above indicators.Conclusion The combined detection of thromboelastography and five coagulation parameters has high predictive value for the prognosis of ACI patients,and provides a basis for early clinical evaluation of the severity of ACI.
acute cerebral infarctionblood coagulation five itemsthromboelastographydegree of illness
万方数据
维普
