Clinical effects of percutaneous introduction of compound ammonium glycyrrhizin solution in the treatment of acne rosacea
Objective To evaluate the clinical efects and safety of percutaneous introduction of compound ammonium glycyrrhizin solution in the treatment of erythema telangiectasia acne rosacea.Methods 75 patients with erythema telangiectasia rose acne were randomly divided into 3 groups.Group A(27 cases)were treated with compound ammonium glycyrrhizin solution combined with external medical cold dressing.Group B(25 cases)were treated with oral compound ammonium glycyrrhizin tablets combined with external medical cold dressing,and the control group(23 cases)were treated with external medical cold dressing only.The treatment cycle of the 3 groups was 4 weeks.Results After treatment,the efficacy of the 3 groups was compared,and the difference was statistically significant(P<0.05).During the trial,2 cases in Group A were experienced transient worsening of symptoms and were subjected to dropout testing.Throughout the treatment process of the three groups of patients,no serious adverse reactions occurred.During the one month follow-up after treatment,there was no statistically significant difference in recurrence rates among the three groups(P>0.05).Conclusion Percutaneous introduction of compound ammonium glycyrrhizin solution in the treatment of erythema telangiectasia rose acne is clinically safe and effective.