Correlation and predictive value of echocardiography,Hcy and PAOI in patients with acute pulmonary embolism
Objective To explore the correlation between echocardiography,serum homocysteine(Hcy)levels and CT pulmonary embolism obstruction index(PAOI)in patients with acute pulmonary embolism(APE),as well as its value in predicting therapeutic efficacy.Methods 149 patients with APE were selected for the study,and were classified as mild(PAOI score<30%)45 cases,moderate(30%≤PAOI score<50%)58 cases,and severe(PAOI score≥50%)46 cases,and the correlation of cardiovascular parameters,serum Hcy level and PAOI at admission and their predictive value of the therapeutic efficacy were analyzed.Results At admission,the right atrial end-systolic diameter(RAESD),right ventricular end-diastolic diameter(RVEDD),main pulmonary artery diameter(MPA),systolic pulmonary artery pressure(SPAP),and Hcy levels were higher in severe patients than in moderate patients and mild patients,and the difference was statistieally significant(P<0.05).At admission,RAESD,RVEDD,MPA,SPAP,and serum Hcy levels were positively correlated with PAOI(P<0.05).Compared with effective patients,the RAESD,RVEDD,MPA,SPAP,and Hcy levels were higher in ineffective patients after 1,2,and 3 weeks of treatment(P<0.05).The ROC curve showed that the AUC of RAESD,RVEDD,MPA,SPAP,and Hcy combined to predict ineffective treatment of APE after 1,2 and 3 weeks of treatment were 0.877,0.922 and 0.934,respectively(P<0.05).Conclusion Echocardiography parameters and Hcy reflect the condition of patients with APE,and when combined,they can predict the risk of ineffective APE treatment,providing guidance for improving treatment plans.
acute pulmonary embolismechocardiographyserum homocysteinepulmonary embolism obstruction index
万方数据
维普
