Clinical effects of Huangkui capsule combined with conventional western medicinein the treatment of children with PNS
Objective To analyze the clinical effects of Huangkui capsule combined with conventional western medicine in the treatment of children with primary nephrotic syndrome(PNS).Methods All 98 children with PNS were divided into the conventional western medicine group and traditional Chinese medicine(TCM)combined group by random number table method.The conventional western medicine group were treated with mycophenolate morphenate and prednisone acetate,while the TCM combined group were treated with Huangkui capsule combined with mycophenolate morphenate and prednisone acetate.After 8 weeks of treatment,the clinical efficacy,renal function indexes,hemorheology indexes,inflammatory factors and the incidence of adverse reactions were compared between the two groups.Results After treatment,the total effective rate of the TCM combined group was 93.88%,which was higher than that of the conventional western medicine group 77.55%,showing a statistically significant difference(P<0.05).After treatment,the clinical efficacy,renal function indexes,hemorheology indexes,inflammatory factors and the incidence of adverse reactions in the TCM combined group were lower than those in the conventional western medicine group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Huangkui capsule combined with prednisone acetate and mycophenol morpheate is effective in the treatment of children with PNS,which can improve renal function and inflammation,reduce hemorheology,and is beneficial to the prognosis of children with high drug safety.
万方数据
维普
