Objective To explore the clinical effect of compound Congrong Yizhi capsule combined with repetitive transcranial magnetic stimulation(rTMS)in the treatment of patients with vascular cognitive impairment of non-dementia(VCIND).Methods 92 patients with VCIND were selected as the study subjects and divided into a control group and an observation group according to the random number table method,with 46 cases in each group.The control group were received conventional drug combined with rTMS treatment,while the observation group were received compound Congrong Yizhi capsule combined with conventional drug and rTMS.The treatment effects of the two groups were compared after 4 weeks of treatment.Changes in cognitive function and activities of daily living were observed before and after 4 weeks of treatment in both groups.The differences in the incidence of adverse reactions between the two groups during treatment were analyzed.Results After 4 weeks of treatment,the treatment effect of the observation group was superior to that of the control group,showing a statistically significart difference(P<0.05).The scores of Mini-Mental State Examination(MMSE),Montreal Cognitive Assessment(MoCA),and Barthel Index(BI)in the observation group were higher than those in the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Compound Congrong Yizhi capsule combined with rTMS can effectively improve cognitive dysfunction in patients with VCIND,enhance activities of daily living,and have good safety.
关键词
复方苁蓉益智胶囊/重复经颅磁刺激/非痴呆型血管性认知障碍/认知功能/日常生活活动能力
Key words
compound Congrong Yizhi capsule/repetitive transcranial magnetic stimulation/vascular cognitive impairment of non-dementia/cognitive function/activities of daily living
维普
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