Clinical efficacy of Xianling Gubao combined with vitamin D2 in the treatment of osteoporosis
Objective To investigate the clinical efficacy of Xianling Gubao combined with vitamin D2 in the treatment of osteoporosis(OP)patients.Methods 90 patients with osteoporosis were selected and randomly divided into two groups using a random number table,with 45 patients in each group.Both groups of patients were treated with Caltech D tablets,with the control group were receiving vitamin D2 soft capsules and the observation group were receiving Xianling Gubao capsules and vitamin D2.After 3 months of continuous treatment,compare the clinical efficacy,bone metabolism indicators,bone turnover indicators,bone density,quality of life,and adverse reactions between the two groups.Results The total effective rate of the observation group was 95.56％,which was higher than 82.22％of the control group.After treatment,the levels of alkaline phosphatase(ALP),bone derived alkaline phosphatase(BAP),osteocalcin(OC),bone density,and the MOS 36-item short-form health survey(SF-36)score in the observation group were higher than those in the control group.The level of type Ⅰ collagen cross-linked C-terminal peptide(CTX-1)was lower than that in the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The combination of Xianling Gubao and vitamin D2 has a better therapeutic effect on OP patients,improving bone density,bone metabolism,and bone turnover,enhancing patients'quality of life,and has good safety.It is worthy of clinical application and promotion.
osteoporosisimmortal spirit bone preservationvitamin D2bone densitybone metabolismbone conversion
万方数据
维普
