Based on the background of launch safety of large-caliber artillery using high-density loaded propellant charge,the effects of crushing of propellant grains and charge structure on interior ballistic characteristics at low-temperature are modeled and simulated.On account of the high-density loaded propellant charge in a large caliber artillery with a central ignition tube,the two-dimensional two-phase flow mathematical model of the ignition tube and the propellant charge was established.Com-bined with the function of stress in propellant grains and fragmentation in the barrel,the numerical difference method was used to simulate the internal ballistic circle,and the effects of the temperature and mixed charge on the crushing of propellant grains and internal ballistic performance of the artillery were studied.The results show that propellant grains in single charge structure will crush,and the degree of crushing increases with the decrease of temperature at low temperature.At-20℃ and-40 C,the maximum degree of crushing reaches 1.896 and 2.487,and the chamber pressure is 690.32 MPa and 803.64MPa respectively,with an increase of 16.4%.When the mass of propellant charge is constant to 6.25kg,the mass of smaller grains increases from 0kg to 0.4kg in mixed charge,the maximum crushing degree decreases from 2.487 to 1.803,and the pressure in the chamber decreases from 803.64MPa to 740.81 MPa.It can be seen that the mixed charge can effectively avoid the breakage of powder particles.