我国吸毒人群艾滋病感染危险因素的Meta分析
Meta-analysis on risk factors of HIV infection among drug users in China
邢健男 1钱莎莎 1郭巍 1李银鸽 2丁正伟 1王璐1
作者信息
- 1. 中国疾病预防控制中心性病艾滋病预防控制中心,北京102206
- 2. Harvard School of Public Health
- 折叠
摘要
目的 综合评价我国吸毒人群艾滋病感染的危险因素,为制定吸毒人群艾滋病综合防治干预策略和措施提供理论依据.方法 系统地收集我国吸毒人群感染艾滋病危险因素的相关研究文献,按照STROBE声明分别对不同研究类型的文献进行质量评价；对数据进行分析,得到合并的OR值及其95％ CI,并进行敏感性分析以及偏倚分析.结果 纳入合格的研究文献14篇,文献质量评价16分以上者7篇,文献质量较高；有统计学意义的危险因素依次为少数民族、共用针具、无工作、注射吸毒及教育程度≤9年,OR值分别为3.08 [1.81,5.24]、4.46[2.71,7.34]、1.34 [1.02,1.76]、3.73[2.95,4.70]和1.32 [1.01,1.74].结论 初步判定少数民族、共用针具、无工作、注射吸毒及教育程度≤9年为我国吸毒人群艾滋病感染的危险因素.
Abstract
Objective To evaluate the risk factors of HIV/AIDS infection among drug users in China and provide theoretical evidence for the development and implementation of HIV/AIDS prevention and intervention strategies in this population.Methods Published literatures about the risk factors of HIV/AIDS among drug users in China were collected systematically and the quality of the literatures was evaluated according to STROBE statement.The data were analyzed to obtain the co-OR and 95％ CI values,and sensitivity and bias analyses were conducted too.Results Fourteen literatures were selected for Meta-analysis.According to the evaluation results,the scores of 7 literatures were ≥ 16,indicating high quality of these literatures.The risk factors with statistical significance were as follows:minority ethnic group,needle sharing,unemployment,injecting drug use and education level ≤9 years; and their OR values were 3.08 (1.81,5.24),4.46 (2.71,7.34),1.34 (1.02,1.76),3.73 (2.95,4.70) and 1.32 (1.01,1.74) respectively.Conclusion The preliminarily analysis indicated that minority ethnic group,needle sharing,unemployment,injecting drug use and education level ≤9 years are the risk factors for HIV/AIDS infection among drug users in China.
关键词
吸毒人群/艾滋病/危险因素/Meta分析Key words
drug user/acquired immunodeficiency syndromes/risk factor/Meta-analysis引用本文复制引用
出版年
2013
NETL
NSTL
维普
万方数据