Epidemiological investigation of two measles cases caused by genotype B3 virus in Hebei,2023
Objective To understand the epidemiological characteristics of two cases of measles in Hebei province in 2023 and provide evidence for the effective prevention and control of the epidemic.Methods Epidemiological investigation was carried out for the two cases.Serum IgM to measles virus was detected by enzyme-linked immunosorbent assay,measles virus nucleic acid was detected by reverse transcription polymerase chain reaction(RT-PCR),and PCR products were sequenced.Results The results of serological test and nucleic acid test of measles virus were positive,and the results of the sequence alignment indicated that pathogen was measles virus B3.Conclusion It was the first time that measles case caused by genotype B3 virus was reported in Hebei.No secondary transmission occurred.
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