首页|减重代谢手术在非酒精性脂肪性肝病患者中的应用

减重代谢手术在非酒精性脂肪性肝病患者中的应用

扫码查看
非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD)是一种与代谢综合征密切相关的慢性肝脏疾病 迄今为止,NAFLD已成为全球最常见的慢性肝病,严重危害人类健康,造成巨大的社会负担.减重代谢手术可显著改善患者的肝脏脂肪变性和炎症,但国内外均没有正式批准用于治疗NAFLD.减重代谢手术治疗NAFLD的确切机制尚不明确,在改变生活方式和药物治疗效果不令人满意的情况下,手术是非常值得考虑的治疗方式.在我国,目前对减重代谢手术治疗NAFLD的相关报道较少,所以本文对其临床有效性、并发症和可能的作用机制等方面进行综述.
APPLICATION OF METABOLIC AND BARIATRIC SURGERY IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE
Non-alcoholic fatty liver disease(nonalcoholic fatty liver disease,NAFLD)is a chronic liver disease closely related to the metabolic syndrome.To date,NAFLD has become the most common chronic liver disease in the world,seriously en-dangering human health and causing a huge social burden.Studies have found that metabolic and bariatric surgery can signifi-cantly improve hepatic steatosis and inflammation in patients,but it is not formally approved for the treatment of NAFLD.The exact mechanism of metabolic and bariatric surgery for NAFLD is still unclear,and the surgery is a very worthwhile treatment to be con-sidered in the case of unsatisfactory lifestyle modification and drug treatment.In China,there are fewer reports related to metabolic and bariatric surgery for NAFLD,so this article reviews its clinical effectiveness,complications and possible mechanisms of action.

metabolic and bariatric surgerynon-alcoholic fatty liver diseaseefficacycomplicationsmechanisn

韩额尔敦、牛剑祥

展开 >

内蒙古医科大学,内蒙古 呼和浩特 010059

内蒙古医科大附属医院肝胆外科,内蒙古 呼和浩特 010050

减重代谢手术 非酒精性脂肪性肝病 疗效 并发症 机制

内蒙古医科大学"致远"人才计划内蒙古医科大学联合项目

ZY0202024YKD2023LH046

2024

疾病监测与控制
中华预防医学会

疾病监测与控制

影响因子:0.41
ISSN:1673-9388
年,卷(期):2024.18(1)