首页|止吐药物与质子泵抑制剂临床药学路径的应用效果分析

止吐药物与质子泵抑制剂临床药学路径的应用效果分析

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目的 分析止吐药物与质子泵抑制剂临床药学路径的应用效果.方法 选取为2022年1月至2023年2月,我院肿瘤内科收治的300例肿瘤患者为研究对象,其中2022年1月到2022年7月,止吐药物与质子泵抑制剂应用常规干预方法,有150例患者纳入研究,设定组名为实施前;2022年8月到2023年2月,止吐药物与质子泵抑制剂应用临床药学路径方法,有150例患者纳入研究,设定组名为实施后.将两组干预效果对照分析.结果 实施后止吐药物与质子泵抑制剂人均药费、销售金额、使用强度、用药频度统计结果均低于实施前,差异有统计学意义(P<0.05);实施后不合理用药发生率、不良反应发生率均低于实施前,差异有统计学意义(P<0.05);实施前以中度不良反应为主,而实施后更优,以轻度不良反应为主,差异有统计学意义(P<0.05);生活质量方面,实施后生理功能、生理职能、总体健康、精神健康、活力、躯体疼痛、情感职能、社会功能评分均比实施前更高,数据差异有统计学意义(P<0.05).结论 通过开展临床药学路径,有助于提升止吐药物及质子泵抑制剂合理用药效果,患者不良反应更少,且严重程度更轻,对提高其生活质量具有很多积极作用,值得普及与使用.
CLINICAL PHARMACY PATHWAY ANALYSIS OF ANTIEMETIC DRUGS AND PROTON PUMP INHIBITORS
Objective To analyze the clinical pharmacy pathway effect of antiemetic drugs and proton pump inhibitors.Methods The study period was from January 2022 to February 2023,and a total of 300 cancer patients admitted to the Depart-ment of Oncology in our hospital were enrolled as the study objects.From January 2022 to July 2022,antiemetic drugs and proton pump inhibitors were used as routine interventions,and 150 patients were enrolled in the study.From August 2022 to February 2023,the clinical pharmacy pathway approach was applied to antiemetic drugs and proton pump inhibitors,and 150 patients were enrolled in the study,setting the group name after implementation.The effect of intervention in the two groups was analyzed.Re-sults After the implementation of antiemetic drugs and proton pump inhibitors per capita drug cost,sales amount,use intensity,frequency statistics were lower than before the implementation(P<0.05);The incidence of irrational drug use and adverse reac-tions were lower after implementation than before implementation(P<0.05).Before implementation,the majority of patients had moderate adverse reactions,but after implementation,the majority of patients had mild adverse reactions(P<0.05).In terms of quality of life,the scores of physiological function,physiological function,general health,mental health,vitality,physical pain,emotional function and social function were higher after implementation than before implementation,and the data were different(P<0.05).Conclusion Through clinical pharmacy pathway,it is helpful to improve the rational drug use effect of antiemetic drugs and proton pump inhibitors,and the adverse reactions of patients are less and the severity is less.

clinical pharmacy pathwayantiemetic drugsproton pump inhibitorsdorasetronrabeprazoleadverse reac-tion

徐军华、罗艳萍、陈清智

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龙岩人民医院 药剂科,福建龙岩 364000

龙岩人民医院 消化科,福建 龙岩 364000

临床药学路径 止吐药物 质子泵抑制剂 多拉司琼 雷贝拉唑 不良反应

龙岩市科技计划项目

FLY2022CWS010121

2024

疾病监测与控制
中华预防医学会

疾病监测与控制

影响因子:0.41
ISSN:1673-9388
年,卷(期):2024.20(3)
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