Clinical Effect of Modified Shenqi Dihuang Decoction on Chronic Kidney Disease Stages 3-4
Objective To investigate the clinical effect of Shenqi Dihuang Decoction on the patients with chronic kidney disease stages 3-4.Methods A total of 60 patients with chronic kidney disease stages 3-4 who were treated in Suzhou Hospital of Traditional Chinese Medicine from January 2019 to May 2023 were assigned by the random number table method into a control group and an observation group,each with 30 patients.On the basis of conventional treatment,the patients in the control group were treated with Shenshuaining tablets,and those in the observation group with modified Shenqi Dihuang Decoction.The levels of serum creatinine(Scr),blood urea nitrogen(BUN),and uric acid(UA)in the two groups were measured.The traditional Chinese medicine(TCM)symptom scores and clinical efficacy were compared between the two groups.Results The total response rate in the observation group was 86.67%,which was higher than that(77.33%)in the control group(P<0.05).After treatment,the observation group had lower levels of Scr,BUN,and UA than the control group(P<0.05).There were differences in the scores of fatigue,poor appetite,waist and knee pain,and limb weakness between the two groups(P<0.01 or P<0.05).Conclusion Shenqi Dihuang Decoction demonstrates definite effects on patients with chronic kidney disease stages 34.It can reduce Scr,BUN,and UA,alleviate clinical symptoms,and delay the progression of chronic kidney disease.