Medication Rule of Traditional Chinese Medicine in Treatment of Essential Thrombocythemia Based on Data Mining
Objective This paper aims to analyze the medication rule of traditional Chinese medicine in the treatment of essential thrombocytopenia(ET).Methods By searching the prescriptions of traditional Chinese medicine for the treatment of ET collected by CNKI and Wanfang database,a database was established and analyzed by the software of"Traditional Chinese Medicine Inheritance Computing Platform system(V3.0)".Results A total of 49 prescriptions were selected,involving 177 drugs,and Ligusticum chuanxiong,Angelica sinensis,Radix Paeoniae Rubra,Semen Persicae,Radix Rehmanniae,Flos Carthami,Salvia miltiorrhiza,and Radix et Rhizoma Glycyrrhizae had the highest frequency.The main medicinal properties were cold,warm,and flat,and the taste of medicine was sweet,bitter,and pungent.In addition,the meridians of the medicine were mainly liver,spleen,and heart.The core combinations of commonly used drugs were obtained based on association rules,including Ligusticum chuanxiong-Radix Paeoniae Rubra,Ligusticum chuanxiong-Flos Carthami,Angelica sinensis-Semen Persicae,Chuanxiong-Angelica sinensis,and Semen Persicae-Flos Carthami.Three groups of potential new core combinations were obtained based on the clustering algorithm.Conclusion The treatment of ET with traditional Chinese medicine mainly focuses on promoting blood circulation and removing blood stasis,clearing heat and cooling blood,and strengthening and consolidating body resistance.
essential thrombocythemiatraditional Chinese medicineTraditional Chinese Medicine Inheritance Computing platformmedication rule
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