首页|中药联合抗肿瘤血管生成药物治疗非小细胞肺癌的研究进展

中药联合抗肿瘤血管生成药物治疗非小细胞肺癌的研究进展

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  • NSTL
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非小细胞肺癌(NSCLC)是肺癌最为常见的一种病理类型，一半以上的患者确诊时即为进展期肺癌，患者生存期较短。抗肿瘤血管生成药物是目前治疗非小细胞肺癌的重要靶向药物，其临床疗效已获得临床认可，但仍存在耐药性及毒副作用不可耐受的局限性，而中药辨证论治及减毒增效的优点，可减轻药物的不良反应，并提高临床疗效，已成为中西医结合治疗非小细胞肺癌的重要方向。本文主要通过检索 2010 年 1 月—2023 年 6 月中国知网、万方、维普及PubMed等数据库中的相关文献，总结近年来不同中药联合各类抗肿瘤血管生成药物治疗NSCLC的相关研究，试从不同角度探讨治疗NSCLC的新思路。
Progress in the Study of Traditional Chinese Medicine Combined with Anti-tumor Angiogenic Drugs in the Treatment of Non-small Cell Lung Cancer
Non-small cell lung cancer(NSCLC)is the most common pathological type of lung cancer,and more than half of the patients are diagnosed with progressive lung cancer,with a shorter survival period.Anti-tumor angiogenic drugs are important target drugs for the treatment of NSCLC,and their clinical efficacy has been clinically recognized.However,they still have the limitations of drug resistance and intolerable toxic side effects,whereas the advantages of traditional Chinese medicine(TCM)in identifying and treating the disease,reducing toxicity,and increasing efficacy can alleviate the adverse effects of the drugs and improve the clinical efficacy,which has become an important direction of traditional Chinese and western medicines in the treatment of NSCLC.This paper mainly searched the relevant literature in the databases of China National Knowledge Infrastructure(CNKI),Wanfang Data,VIP,and PubMed from January 2010 to June 2023 and summarized the relevant studies on different traditional Chinese medicines combined with various types of anti-tumor angiogenic drugs in the treatment of NSCLC in recent years,so as to explore the new ideas for the treatment of NSCLC from different perspectives.

non-small cell lung cancertraditional Chinese medicineanti-tumor angiogenic drugscombination therapy

刘宝生、周秀丽、朱彦、刘丽红、于泽胜、王振华

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潍坊市中医院临床药学科(山东 潍坊 261000)

潍坊市人民医院临床药学科(山东 潍坊 261000)

中国中医科学院中医药信息研究所 (北京 100700)

非小细胞肺癌 中药 抗肿瘤血管生成药物 联合治疗

国家自然科学基金资助项目潍坊市卫生健康委员会科研项目潍坊市卫生健康委员会中医药科研项目中国毒理学会临床毒理专项研究课题潍坊市科技发展计划(软科学)

82274684WFWSJK-2022-2792022年第4类第50号CST2019CT3072022RKX066

2024

10.20065/j.cnki.btcm.20240044

基层中医药
中国中医科学院中医研究所

基层中医药

ISSN：2097-1222
年,卷(期)：2024.3(2)
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