Clinical Observation of Modified Maiwei Dihuang Decoction Combined with Chemotherapy in Treating Lung Squamous Cell Carcinoma with Yin Deficiency of Lung and Kidney
Objective To observe the clinical efficacy of modified Maiwei Dihuang Decoction combined with chemotherapy in the treatment of lung squamous cell carcinoma with Yin deficiency of lung and kidney.Method Sixty patients suffering from lung squamous cell carcinoma with Yin deficiency of lung and kidney were selected and randomly divided into a control group and an observation group,with 30 cases in each group.The control group received GP regimen chemotherapy and supportive symptomatic treatment.The observation group was treated with modified Maiwei Dihuang Decoction on the basis of the control group.21 days is considered as one cycle,and the efficacy was evaluated after two cycles.The clinical efficacy,changes in traditional Chinese medicine(TCM)clinical syndromes,adverse reactions,and quality of life in the two groups were observed after treatment.Results The quality of life in the observation group was improved and better than that in the control group before and after two cycles of treatment,and the difference between the two groups was statistically significant(P<0.05).After treatment,the overall improvement rate of TCM syndrome efficacy was compared,and the observation group was better than the control group(P<0.05).The observation group showed better improvement in white blood cell count,platelet count,and incidence of gastrointestinal reactions than the control group(P<0.05),and the total effective rate of treatment in the observation group was better than that in the control group(P<0.05).Conclusion Modified Maiwei Dihuang Decoction combined with chemotherapy can enhance clinical efficacy,improve clinical symptoms,reduce adverse reactions,and elevate the quality of life in the treatment of lung squamous cell carcinoma with Yin deficiency of lung and kidney.
lung squamous cell carcinomaYin deficiency of lung and kidneymodified Maiwei Dihuang Decoctionchemotherapyclinical efficacy