Clinical Observation on Shuanghuang Shengbai Granules in Prevention and Treatment of Myelosuppression after Chemotherapy for Lung Cancer in the Patients with Essential Qi Deficiency
Objective To observe the clinical effect of Shuanghuang Shengbai Granules on myelosuppression after chemotherapy for lung cancer in the patients with essential qi deficiency.Methods Ninety-two patients with lung cancer due to essential qi deficiency treated in Pudong New Area Hospital of Traditional Chinese Medicine from October 2019 to June 2022 were selected and assigned into a treatment group and a control group by completely randomized design.The treatment group was treated with Shuanghuang Shengbai Granules since the first day of chemotherapy,while the control group was administrated with Leucogen while receiving chemotherapy.After 14 days of treatment,the clinical effects and safety in both groups were evaluated.Results The decreases of white blood cells and neutrophils after chemotherapy in the treatment group were lower than those in the control group(P<0.05).The treatment group outperformed the control group in alleviating the TCM syndrome(P<0.01)and increasing the KPS score(P<0.05).Conclusion Shuanghuang Shengbai Granules can prevent and treat myelosuppression after chemotherapy for lung cancer in the patients with essential qi deficiency.
Shuanghuang Shengbai Granuleslung canceressential qi deficiencymyelosuppression after chemotherapy
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