Medication Rules of Traditional Chinese Medicine in the Treatment of Varicocele Based on Data Mining
Objective To explore the clinical medication rules of traditional Chinese medicine(TCM)in the treatment of varicocele(VC)using data mining.Methods Literature on the treatment of VC with TCM was searched in the China National Knowledge Infrastructure(CNKI),Wanfang Data Knowledge Service Platform,and CQVIP databases from their inception to August 2023.Prescription data were selected and standardized using Excel,then input into the Traditional Chinese Medicine Inheritance Support Platform(V2.5)for analysis.The analysis focused on TCM syndromes,medication frequency,flavor and meridian tropism,prescription rules,and new prescriptions to summarize and study the medication rules of TCM in the treatment of VC.Results A total of 80 qualified prescriptions from 60 pieces of literature were included,comprising 147 drugs.The most frequently identified TCM syndromes were kidney deficiency and blood stasis syndrome,blood stasis obstructing the collaterals syndrome,qi deficiency and blood stasis syndrome,and qi stagnation and blood stasis syndrome.Eleven drugs had a frequency of 20 or more,which were warm in nature and sweet in flavor and acted on liver,kidney,and spleen meridians.The most frequently used herbal pairs were Cuscutae Semen-Lycii Fructus and Salviae Miltiorrhizae Radix et Rhizoma-Angelicae Sinensis Radix,with the highest confidence in the use of Epimedii Folium,Lycii Fructus,and Cuscutae Semen.Thirteen new prescriptions were recombined.Conclusion Currently,TCM treatment of VC primarily focuses on promoting blood circulation and removing blood stasis,while also considering kidney tonifying,liver soothing,spleen strengthening,qi regulation,and qi tonifying.
varicoceletraditional Chinese medicinedata miningmedication rule