Study on Medication Rules of Traditional Chinese Medicine Compound for Hypertension Based on National Patent
Objective To analyze the prescription rules of Chinese medicine compound patents for the treatment of hypertension based on data mining,and to provide reference for the research and development of new drugs.Methods The data related to the treatment of hypertension by compound prescription from the establishment of the database to April 2023 by the State Intellectual Property Office were retrieved and entered.The Traditional Chinese Medicine Inheritance Auxiliary Platform(V2.5)and IBM SPSS Modeler 18.0 were used to conduct drug frequency,association rules and entropy cluster analysis on the compound patent that met the inclusion criteria.Results A total of 866 compound patents were included,covering 941 Chinese medicines.High frequency single herb include Uncaria,Prunella,Salvia,etc.;High frequency medicines are Prunella-Uncaria,Uncaria-Gastrodia,etc.;The most commonly used horn medicine is Danshen-Gouteng-Tianma;Association rule analysis Uncaria was closely related to Sangjisheng,Tianma,Shijueming,Huangqin and other medicines.Entropy clustering extraction core drug combination around the wind,fire,.phlegm,blood stasis,deficiency pathological factors legislation.Conclusion The analysis results show that the diagnosis and treatment of hypertension in traditional Chinese medicine is mainly based on the treatment of liver fire,taking into account other organs,combined with the method of resolving phlegm and activating blood,regulating yin and yang,treating the disease and taking into account the specimen.
Data mininghypertensionmedication rulesTraditional Chinese Medicine Inheritance Support Platform
NETL
NSTL
万方数据
