Meta-analysis of Qiju Dihuang Pills Combined with Tianma Gouteng Yin for Treating Hypertension
Objective To systematically evaluate the efficacy and safety of Qiju Dihuang pills combined with Tianma Gouteng yin in treating hypertension.Methods Performing a systematic database search for published randomized controlled trials investigating the efficacy of Qiju Dihuang pills combined with Tianma Gouteng yin in treating hypertension,extracting data,and conducting a meta-analysis.Results A total of 31 studies involving 3 783 hypertensive patients were included.Meta-analysis results revealed that the combined therapy of Qiju Dihuang pills and Tianma Gouteng yin significantly surpassed conventional western medicine in terms of reducing blood pressure[SBP:MD=12.11,95％CI(10.11,14.10);DBP:MD=8.48,95％CI(6.91,10.06)]and efficacy rate[RR=1.18,95％CI(1.15,1.21)],with a notably lower incidence of adverse reactions compared to conventional western medicine[RR=0.41,95％CI(0.31,0.53)].Compared to the combined use of Qiju Dihuang pills with Tianma Gouteng yin alone,the combination with conventional western medicine did not significantly enhance the antihypertensive and therapeutic effects.Instead,it resulted in a 1.93-fold increase in the incidence of adverse reactions.Conclusion The efficacy and safety of Qiju Dihuang pills combined with Tianma Gouteng yin in treating hypertension are superior to conventional western medicine treatment.However,when used in combination with conventional western medicine,attention should be paid to the risk of adverse reactions.
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