Research Progress on the Regulation of Apoptosis Pathway by Active Ingredients of Traditional Chinese Medicine in Intervening Pathological Scars
Various active ingredients such as terpenes,flavonoids,alkaloids,steroids,phenolic acids and bile acids in traditional Chinese medicine can induce excessive proliferation of fibroblasts through apoptosis,reduce pathological accumulation of extracellular matrix,and thus play a role in treating pathological scars.Therefore,the role of apoptosis pathways in pathological scars in recent years and the research progress on the intervention of traditional Chinese medicine active ingredients are reviewed,in order to provide ideas for the development of new drugs for treating pathological scars.
Traditional Chinese medicinepathologic scarapoptosis pathwaymechanismresearch progress