首页|吴茱萸汁的制备工艺及吴茱萸汁制远志的炮制工艺优化

吴茱萸汁的制备工艺及吴茱萸汁制远志的炮制工艺优化

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目的 优选吴茱萸汁的制备工艺以及吴茱萸汁制远志的炮制工艺.方法 采用层次分析法(AHP)、多指标综合评分法结合正交试验,以吴茱萸碱、吴茱萸次碱、去氢吴茱萸碱、吴茱萸卡品碱、柠檬苦素和煎膏率为评价指标,考察加水量、浸泡时间和煎煮时间对吴茱萸汁的制备工艺的影响;以细叶远志皂苷、远志(口山)酮Ⅲ、3,6'-二芥子酰基蔗糖、远志皂苷B、远志酸、远志皂苷元、吴茱萸碱、吴茱萸次碱、去氢吴茱萸碱为评价指标,考察料液比、炒制温度和炒制时间对吴茱萸汁制远志的影响.结果 吴茱萸汁的最佳制备工艺为提取三次,每次加水量为药材的12倍,浸泡60 min,煎煮50 min.吴茱萸汁制远志的最佳工艺为取远志加入1.5倍量吴茱萸汁,140℃炒制8 min.结论 对规范吴茱萸汁制备工艺以及吴茱萸汁制远志炮制工艺具有一定的指导意义,为中药远志的炮制工艺优化提供参考.
Optimization of the Preparation Process of Evodia Juice and the Concoction Process of Yu-yuanzhi by Orthogonal Experiment Combined with AHP Method
Objective To optimize the preparation process of Evodia juice and the processing technique of combining it with Polygala tenuifolia.Methods Using the Analytic Hierarchy Process(AHP),Multi-Criteria Decision Analysis(MCDA),and combining L9(34)orthogonal text,the impact of water volume,soaking time and extraction time on the preparation process of Evodia juice was investigated,with evodiamine,rutaecarpine,dehydroevodiamine,wuzhuyu capilline,limonin,and decoction yield as the observed index.Similarly,the effects of Liquid-to-material ratio,roasting temperature and roasting time on the preparation of Polygala tenuifolia combined with Evodia juice were studied,with tenuifolin,polygalaxanthone Ⅲ,3,6'-disinapoyl sucrose,onjisaponin B,polygalacic acid,senegenin,evodiamine,rutaecarpine and dehydroevodiamine as the observed index.Results The optimal preparation process for Evodia juice was as follows:extraction performed three times,with a water volume of 12 times the amount of medicinal materials,soaking for 60 min,and extraction for 50 min.The best technique for combining Evodia juice with Polygala tenuifolia was to take Polygala tenuifolia and add 1.5 times the amount of Evodia juice,roasting at 140℃ for 8 minutes.Conclusion This experiment holds significance in standardizing the preparation process of Evodia juice and the processing technique of combining it with Polygala tenuifolia,which provide reference for the optimization of processing technology of traditional Chinese medicine Yuanzhi.

Polygala tenuifoliaevodia vulgarisdrug decoction preparation methodorthogonal textanalytic hierarchy process

姚怡、林桂梅、余远盼、李医名、鞠成国

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辽宁中医药大学药学院,辽宁大连 116600

国家中医药管理局中药炮制技术传承基地(辽宁),辽宁 大连 116600

远志 吴茱萸 药汁制法 正交试验 层次分析法

国家中医药管理局中药炮制技术传承创新项目

GZY-KJS-2022-049

2024

现代中药研究与实践
安徽中医药高等专科学校,

现代中药研究与实践

CSTPCD
影响因子:0.409
ISSN:1673-6427
年,卷(期):2024.38(3)
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