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A review on reactive oxygen species-induced mechanism pathways of pharmaceutical waste degradation:Acetaminophen as a drug waste model

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A review on reactive oxygen species-induced mechanism pathways of pharmaceutical waste degradation:Acetaminophen as a drug waste model
Innately designed to induce physiological changes,pharmaceuticals are foreknowingly haz-ardous to the ecosystem.Advanced oxidation processes(AOPs)are recognized as a set of contemporary and highly efficient methods being used as a contrivance for the removal of pharmaceutical residues.Since reactive oxygen species(ROS)are formed in these processes to interact and contribute directly toward the oxidation of target contaminant(s),a profound insight regarding the mechanisms of ROS leading to the degradation of pharmaceuticals is fundamentally significant.The conceptualization of some specific reaction mechanisms allows the design of an effective and safe degradation process that can empirically reduce the environmental impact of the micropollutants.This review mainly deliberates the mech-anistic reaction pathways for ROS-mediated degradation of pharmaceuticals often leading to complete mineralization,with a focus on acetaminophen as a drug waste model.

Wastewater treatmentIonic liquidHydroxyl radicalSuperoxidePharmaceutical contaminantAdvanced oxidation processDeep eutectic solventHydrogen peroxide

Saba Humayun、Maan Hayyan、Yatimah Alias

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Department of Chemistry,Faculty of Science,University of Malaya,Kuala Lumpur 50603,Malaysia

University of Malaya Centre for Ionic Liquids,University of Malaya,Kuala Lumpur 50603,Malaysia

Chemical Engineering Program,Faculty of Engineering and Technology,Muscat University,Muscat P.C.130,Oman

Wastewater treatment Ionic liquid Hydroxyl radical Superoxide Pharmaceutical contaminant Advanced oxidation process Deep eutectic solvent Hydrogen peroxide

2025

10.1016/j.jes.2023.11.021

环境科学学报(英文版)
中科院生态环境研究中心

环境科学学报(英文版)

影响因子：0.862
ISSN：1001-0742
年,卷(期)：2025.147(1)