Effects of Prone Position Ventilation on Delirium in Patients with Severe Pneumonia
Objective To explore the effects of prone position ventilation on delirium in patients with se-vere pneumonia and hypoxaemia.Methods Retrospective analysis was used to analyze 106 patients with se-vere pneumonia,who were admitted to the intensive care unit of a tertiary hospital in Shanghai from De-cember 2022 to January 2023.They were divided into a prone position ventilation(PPV)group(n=54)and a control group(in the supine position,n=52).The patients'basic condition,vital signs,laboratory tests,and complications were analyzed.Results After 3 and 7 days of prone position ventilation,the inci-dence of delirium,the level of CRP,IL-6,IL-8 and TNF-αin the PPV group were lower than those of the control group(all P＜0.05).P/F in PPV group showed an increasing trend and the difference between the two groups was statistically significant(all P＜0.05).The overall inflammatory factors in PPV group showed a decreasing trend and the difference between the two groups was statistically significant(all P＜0.05).Conclusions Prone position ventilation may reduce the incidence of delirium in patients with severe pneumonia by inhibiting inflammation and improving oxygenation.
severe pneumoniaprone position ventilationdeliriumhypoxiainflammatory factornursing
NETL
NSTL
万方数据
维普
