The Application of Multiphase Optimization Strategy in Multifactorial Interventions for Chronic Diseases:A Scoping Review
Objective To understand the application stages and effects of the Multiphase Optimization Strategy(MOST)in multifactorial intervention for chronic diseases,so as to provide suggestions for the building of a multifactorial intervention model for chronic diseases in China,as well as the continual improvement of MOST.Methods According to the methodology framework of scoping review,relevant literatures in 8 Chinese and English databases were systematically searched from the databases'inception to December 22,2023.Results A total of 16 literatures were included,including 10 studies on cancer,2 studies on diabetes,1 study on hypertension,1 study on post acute coronary syndrome(Post-ACS),1 study on cardiopulmo-nary failure and 1 study on asthma.It is mostly used to optimize complex nursing programs and health education leaflets that required co-management of multiple factors such as psychological issues and symptom management.The main advantage of MOST is that it can evaluate the effect of a single intervention component,and the disadvantage is that it lacks objectivity and scientific standards.Conclusions The application of MOST in multifactorial intervention of chronic diseases is still in its infan-cy,and the research programs in each stage need to be further implemented.Future developments in the MOST should be pur-sued in order to fully realize its benefits and encourage the availability of multifactorial management plans for chronic illnesses.