Evaluation of Effect of Microenvironment pH Value Modulation on Wound Healing of Diabetic Foot Ulcer
Objective To evaluate the effect of pH value modulation on the treatment of diabetic foot ulcers.Methods Patients who visited the Diabetes Foot Multidisciplinary Joint Clinic of a tertiary A hospital in Shanghai were randomly di-vided into the intervention group and the control group.The control group received routine nursing care for diabetic foot ul-cer and the intervention group received acidic liquid dressing to adjust the pH value of the wound according to the pH val-ue of the wound.The pH value of the wound,PUSH score and wound healing rate were compared between the two groups before and after the intervention.Results Before intervention,the pH value of the two groups of wounds was in the alka-line range.The pH value and wound area of the intervention group were smaller than those of the control group in the 2nd,4th and 8th week after the intervention.The time required to achieve 50％healing of the intervention group was shorter than that of the control group.At the end of the observation period,the wound healing rate of the intervention group was higher than that of the control group and the differences were statistically significant(all P＜0.05).Conclusions The mod-ulation of the pH value of diabetic foot ulcers can shorten the time of wound healing,reduce infection grading,and improve the wound healing rate,which plays an important role in promoting the healing of diabetic foot ulcers.
万方数据
维普
