Expert Consensus on Nursing Practices of Phage Therapy for Multi-Drug Resistant Organisms Infection Within the Framework of Clinical Trials
Objective To establish the Expert Consensus on Nursing Practices of Phage Therapy for Multi-drug Resistant Organisms Infection within the Framework of Clinical Trials(hereinafter referred to as the Consensus),aiming to standardize the nursing practice of phage therapy for multi-drug resistant organisms infection within the framework of clinical trials.Methods A consensus construction group was established to develop the initial version of the consensus through literature review and clinical stakeholder interviews.The final version of the consensus was formed through two rounds of Delphi expert consultations and four rounds of group meetings.Results This consensus focuses on three stages:pre-treatment,during treat-ment,and post-treatment.It includes clinical research nurse responsibilities and qualifications,patient as-sessment and enrollment,treatment environment preparation,phage preparation,administration according to treatment protocols,implementation and supervision of infection control measures,observation and mo-nitoring,follow-up and tracking,data recording and management.Conclusions The Consensus integrates literature reports,clinical experience,and expert recommendations.It is scientifically grounded and practi-cal,providing guidance for clinical nurses in the treatment of multi-drug resistant organisms infection using phage therapy within the framework of clinical trials.
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