Risk Prediction Model of Cognitive Impairment after Ischemic Stroke:A Systematic Review
Objective To systematically evaluate the risk prediction model of cognitive impairment after is-chemic stroke,so as to provide reference for the prediction of cognitive function in such patients and the construction and application of related models.Methods A computerized search of CNKI,Wanfang,VIP,CBM,PubMed,EMbase,the Cochrane Library,and Web of Science was conducted to collect studies on the risk prediction model of cognitive impairment after ischemic stroke,with the timeframe from the inception to May 2023.Two evaluators screened the literature,extracted information,and evaluated the risk of bias and applicability of the included studies.Results A total of 16 studies on predictive modeling of cognitive impairment in patients after ischemic stroke were included.The overall risk of bias of the included models was high,the applicability of 5 studies good,the applicability of 11 studies poor,and the area under the working characteristic curve of the subjects ranged from 0.708 to 0.913.The common predictors were age,level of education,NIHSS scores,and infarct zonation,etc.The main high risk of bias for inclusion in the model was in the domain of the study subjects and statistical analysis.Conclusions The overall perform-ance of the existing models for predicting the risks of cognitive impairment after ischemic stroke is poor,and the clinical applicability value of the models needs to be further validated.
万方数据
维普
