Network Analysis of Contemporaneous Symptoms in Middle-aged and Young Patients with Heart Failure
Objective To investigate the incidence and severity of symptoms in middle-aged and young pa-tients with heart failure(HF),construct a symptom network for these patients,analyze its central indices,and to explore core symptoms and targets for symptom intervention.Methods A total of 973 middle-aged and young patients with HF were selected to investigate the incidence and severity of symptoms using the Chinese version of the Memorial Heart Failure Symptom Assessment Scale.A regularized partial correla-tion network analysis was used to construct a symptom network and explore its central indices.Results The most common symptom of young and middle-aged patients with chronic heart failure was chest pain(75.8%),and the most serious symptom was lethality/inactivity.The network showed lack of appetite(rs=13.90,rc=0.0129)was the most obvious symptom in strength and closeness among central indices.Sadness(59.4%)was more predictable.Conclusions Intervention on lack of appetite can effectively reduce the severity of the entire network.Early intervention in lethality/inactivity can alleviate the symptoms.Identifying symptoms with strong predictability helps in selecting targets for intervention.Medical staff should implement scientific and accurate symptom management for patients with HF.
young and middle-aged patientheart failurecore symptomnetwork analysissymptom man-agement