Association Between Frailty and Incidence of Chronic Lung Disease Among Middle-Aged and Elderly People in Chinese Community:A Longitudinal Study Based on CHARLS Data
Objective To understand the occurrence of frailty in the middle-aged and elderly population in China,and to explore the correlation between frailty and the incidence of chronic lung disease(CLD).Meth-ods The data of the China Health and Retirement Longitudinal Study(CHARLS)in 2011 and 2018 was used to select 2073 middle-aged and elderly people aged 45 years and over.The Physical Frailty Phenotype(PFP)scale was used to assess the frailty status of the subjects,and the population was categorized into three groups:no frailty,pre-frailty status,and frailty status.The outcome variable of the study was the inci-dence rate of CLD.Weighted Cox proportional risk regression model was used to analyze the association be-tween the frailty phenotype and the risk of CLD.Results A total of 127(6.13%)subjects suffered from CLD.The cumulative prevalence of CLD in the no-frailty,pre-frailty,and frailty groups was 5.05%(14/277),5.63%(87/1544),and 10.32%(26/252),respectively.Compared with the no-frailty group,the frailty group had a higher risk of developing CLD[HR:2.09,95%CI(1.09,4.01),P<0.05].Conclusions There is association between frailty status and risk of developing CLD in the middle-aged and elderly population in the Chinese community.It is suggested that the healthcare personnel should strengthen the frailty assess-ment for the middle-aged and elderly and take intervention measures as early as possible to reduce the inci-dence of CLD.
middle-aged and elderly peoplefrailty phenotypechronic lung disease