光学相干层析成像在生物医学中的研究进展
Research Progress of Optical Coherence Tomography in Biomedicine
颜佳涛 1唐云 1袁锐 2邹鹏辉 1廖萍 1李菁锋 1彭旭翔1
作者信息
- 1. 湖南科技大学物理与电子科学学院智能传感器与新型传感材料湖南省重点实验室,湖南 湘潭 411201
- 2. 谢菲尔德大学电子与电气工程系,英国 谢菲尔德 S10 2TN
- 折叠
摘要
光学相干层析成像(OCT)是近年来发展迅速的一种无损低相干生物医学成像技术.由于能够检测生物组织的微观结构信息,其为生物医学基础和临床研究带来了极大的便利.OCT在眼科中从最初黄斑结构的探索到评估视网膜和脉络膜血管系统,实现了动态结构与静态组织的对比.此外基于光源突破性的发展,OCT系统可能成为皮肤科、胃肠疾病和心血管疾病等多个临床领域的标准检查方法.本文回顾OCT的发展历程,并对各个类别的OCT系统进行介绍,对其成像原理、性能、优缺点等进行描述和对比,最后总结和展望该技术在生物医学的应用.
Abstract
Optical coherence tomography(OCT)is a nondestructive low-coherence biomedical imaging technology that has developed rapidly in recent years.Owing to its ability to detect the microstructure information of biological tissues,OCT has brought great convenience to biomedical basic and clinical research.OCT has helped to achieve a comparison between dynamic and static structures in ophthalmology,from exploring the initial macular structure to evaluating the retinal and choroidal vascular systems.Additionally,with the development of light sources,the OCT system has become a standard examination method in multiple clinical fields,such as dermatology,gastrointestinal diseases,and cardiovascular diseases.Our article reviews the development of OCT,introduces various types of OCT systems,and compares their imaging principles,performance,advantages,and disadvantages.Finally,the summary and prospective applications of this technology in biomedicine are presented.
关键词
光学相干层析成像/生物医学光学/无损检测/三维重建/生物组织Key words
optical coherence tomography/biomedical optics/non-destructive testing/3D reconstruction/biological tissue引用本文复制引用
基金项目
国家自然科学基金青年项目(62005078)
湖南省教育厅科学研究青年项目(21B0477)
湖南科技大学智能传感器与新型传感材料湖南省重点实验室开放基金项目(E22341)
出版年
2024
NETL
NSTL
万方数据