摘要
目的:探究急性脑栓塞病人治疗期间采用低分子肝素、阿司匹林联合用药方案的作用效果.方法:以2021年2月至2022年6月为研究时间区间,选取100例急性脑栓塞病人,以随机数字表法为依据将研究对象分为两组,各50例.对照组单独应用阿司匹林完成治疗,观察组采用低分子肝素、阿司匹林联合用药方案完成治疗,比较两组患者临床治疗效果、神经功能改善情况、昏迷改善情况、日常生活能力改善情况、并发症发生情况以及护理满意度.结果:与对照组患者比较,观察组治疗总有效率显著较高,具备统计学价值(P ＜ 0.05).治疗前,神经功能
Abstract
Objective To investigate the effect of the combination of low-molecular-weight heparin and aspirin in the treatment of patients with acute cerebral embolism.Methods: From February 2021 to June 2022, 100 patients with acute cerebral embolism were selected and divided into two groups based on random number table, 50 patients in each group.The control group was treated with aspirin alone, and the observation group was treated with low-molecular-weight heparin and aspirin combined.The clinical treatment effect, improvement of neurological function, improvement of coma, improvement of ability of daily living, occurrence of complications and satisfaction of nursing were compared between the two groups.Results Compared with the control group, the total effective rate of the observation group was significantly higher, with statistical value (P＜0.05).Before treatment, there was no significant difference in the score of nerve function defect (NIHSS) (P＞0.05). After treatment, the score of NIHSS in both groups was lower than that in the control group, and the difference was significant in the observation group (P＜0.05).Before treatment, there was no significant difference between GCS score and ADL score (P＞0.05).After treatment, both GCS score and ADL score in the two groups were higher than those in the control group and the observation group (P＜0.05).The incidence of complications[rash, bleeding, gastrointestinal reaction]in the observation group was significantly lower than that in the control group (P＜0.05).Conclusion: The clinical effect of the combination of low-molecular-weight heparin and aspirin in the treatment of patients with acute cerebral embolism is outstanding, which is not only conducive to improving the neurological function of patients, but also can improve the coma symptoms and daily living ability of patients, with high safety.It is recommended to promote the clinical application.
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