Objective To investigate the effect of tiotropium bromide powder combined with doxofylline on the improvement of pulmonary function in patients with chronic obstructive pulmonary disease (COPD). Methods: 50 patients with chronic obstructive pulmonary disease who were treated in our hospital were selected as the study objects. The time range of this study was from September 2019 to December 2021.12. They were randomly divided into two groups, namely, the experimental group (n=25) and the reference group (n=25). The patients in the reference group were treated with doxofylline, while the patients in the experimental group were treated with tiotropium bromide powder and doxofylline. The research indicators of this experiment include: lung function related indicators, quality of life related indicators, clinical efficacy and adverse reaction rate. Results: After giving corresponding clinical treatment to the two groups of patients, the relevant inspection indexes of the patients in the experimental group were significantly better than those in the reference group; In terms of therapeutic effect, the patients in the experimental group (96.00％) were better than those in the reference group (68.00％). In terms of the incidence of adverse reactions, the patients in the experimental group (8.00％) were significantly lower than those in the reference group (40.00％), with a significant difference (P＜0.05). Conclusion: For patients with COPD, tiotropium bromide powder combined with doxofylline can significantly improve the lung function related indicators of patients, improve the clinical treatment effect, and has high clinical application value.
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