Objective To analyze the effect of non-invasive high-frequency oscillatory ventilation on neonatal respiratory distress syndrome. Methods: 60 cases of neonatal respiratory distress syndrome in our hospital were randomly divided into control group and experimental group. The traditional ventilation intervention in the control group and non-invasive highfrequency oscillatory ventilation intervention in the experimental group were compared. Results: The time of mechanical ventilation, total oxygen use, and total feeding in the experimental group were significantly lower than those in the control group, and the satisfaction was higher than that in the control group. PaO2 in the experimental group was significantly higher than that in the control group. PaCO2, OI, and hospital stay in the experimental group were significantly lower than those in the control group. The adverse reactions in the experimental group were 6.66％, the treatment effect was 96.66％, the adverse reactions in the control group were 20.00％, and the treatment effect was 83.33％. The difference was statistically significant (P＜0.05). Conclusion: The clinical treatment pressure of neonatal respiratory distress syndrome is high, and the patient''s ventilation function is greatly affected. The non-invasive high-frequency oscillatory ventilation mode can significantly improve the patient''s ventilation effect, which deserves attention.
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