Objective To investigate the difference of therapeutic effects of different triple therapies on duodenal ulcer (DU) patients with Helicobacter pylori (Hp) positive.Methods: 120 patients with Hp positive DU admitted from August 2021 to August 2022 were randomly divided into 60 groups.All patients were treated with clarithromycin and amoxicillin.Based on this, the control group and the observation group were treated with omeprazole and rabeprazole respectively to compare the efficacy of the two groups.Results: Compared with the control group, the total effective rate and Hp eradication rate of the observation group after treatment were higher, the ulcer healing and Hp eradication time were shorter, the adverse reaction rate and CRP, IL-6, TNF- α The level was lower (P＜0.05).Conclusion: Rabeprazole triple therapy is effective and safe in the treatment of Hp positive DU patients.
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