Objective To explore the analysis of patients with acute myocardial infarction combined with clopidogrel and aspirin treatment effect,and its serum IL-6,IL-10 levels. Methods: A total of 120 patients with acute myocardial infarction admitted to the emergency department of our hospital from May 2021 to May 2022 were randomly divided into a control group (aspirin treatment,n=60 cases) and a research group (clopidogrel and aspirin combined treatment,n=60 cases). The therapeutic effects of the two groups were compared,and the cardiac function indicators and serum IL-6 and IL-10 levels before and after treatment in the two groups were measured and evaluated. Results The total effective rate of treatment in research group was 93.33％,which was higher than that in control group (P＜0.05). The left ventricular ejection fraction in the treatment group was (43.04±2.89)％ higher than that in the control group,while the left ventricular end systolic diameter and left ventricular end diastolic diameter,both of which were (53.52±4.48) and (42.26±3.53)mm,were lower than those in the control group (P＜0.05). Moreover,after treatment,the level of IL-6 in the study group was (19.48±1.49)pg/ml/mL,lower than that in the control group,while the level of IL-10,at (6.71±0.94) ng/ml/mL,was higher than that in the control group (P＜0.05). Conclusion: The combined use of clopidogrel and aspirin in patients with acute myocardial infarction has a reliable effect,can significantly improve the patient''s cardiac function,and reduce inflammatory response,which is worthy of promotion.
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