摘要
目的:对乙型肝炎相关肝癌患者使用凝血四项指标以及肿瘤标志物进行检验的诊断效果做出分析.方法:采用2019年1月-2021年12月这一时间段在本院诊治的乙型肝炎相关肝癌患者作为研究对象,总例数66例,作为研究组,另选取同期在我院进行治疗的良性肝病患者作为研究对象,总例数66例,作为常规组,对比分析两组患者在凝血四项指标、肿瘤标志物检测下的诊断效果,包括凝血四项指标水平和阳性率、肿瘤标志物指标水平和阳性率四方面.结果:研究组凝血酶原时间、活化部分凝血活酶时间、凝血酶时间均高于常规组(T=10.199,32.5
Abstract
Objective To analyze the diagnostic effect of four coagulation indicators and tumor markers in patients with hepatitis B related liver cancer.Methods: The patients with hepatitis B related liver cancer diagnosed and treated in our hospital during the period from January 2019 to December 2021 were taken as the study subjects, with a total of 66 cases as the study group.The patients with benign liver disease who were treated in our hospital during the same period were selected as the study subjects, with a total of 66 cases as the routine group.The diagnostic effects of the two groups of patients under the detection of four coagulation indicators and tumor markers were compared and analyzed, It includes the level and positive rate of four indicators of blood coagulation, the level and positive rate of tumor markers.Results: The prothrombin time, activated partial thromboplastin time and thrombin time in the study group were higher than those in the conventional group (T=10.199, 32.544, 19.005, P＜0.001), and the fibrinogen level was lower than that in the conventional group (T=29.254, P＜0.001); The positive rate of four coagulation indexes in the study group was higher than that in the routine group (χ2=4.117, 4.586, 4.264, 4.789, P=0.042, 0.032, 0.038, 0.028); The levels of alpha fetoprotein, vascular endothelial growth factor and fucosylase in the study group were higher than those in the conventional group (T=78.496, 52.207, 58.541,P＜0.001); The positive rate of tumor markers in the study group was higher than that in the conventional group (χ2=5.113, 4.551, 4.117, P=0.023, 0.033, 0.042).Conclusion: The detection of four coagulation indexes and tumor markers in patients with hepatitis B related liver cancer shows positive results, which can effectively distinguish them from benign liver diseases, with high clinical application value.
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