健康大视野·医学分册2023,Issue(10) :1-2.DOI:10.3969/j.issn.1005-0019.2023.10.001

左氧氟沙星联合抗结核方案应用于肺结核治疗的效果观察

Effect observation of levofloxacin combined with anti-tuberculosis regimen in the treatment of pulmonary tuberculosis

郝浩 齐鲁钰 刘其亳
健康大视野·医学分册2023,Issue(10) :1-2.DOI:10.3969/j.issn.1005-0019.2023.10.001

左氧氟沙星联合抗结核方案应用于肺结核治疗的效果观察

Effect observation of levofloxacin combined with anti-tuberculosis regimen in the treatment of pulmonary tuberculosis

郝浩 1齐鲁钰 1刘其亳1
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作者信息

  • 1. 聊城市传染病医院胸内科,山东 聊城 252000
  • 折叠

摘要

目的:探讨对肺结核患者采用左氧氟沙星+抗结核方案完成治疗后获得临床效果.方法:选取我院时间范围处于2020年2月~2022年5月阶段的80例肺结核患者作为研究对象;以随机数字表法作为治疗研究分组依据,并展开所有肺结核患者不同组别划分;其中选择常规抗结核方案治疗的设为参照组(n=40);在参照组常规方案基础上,选择左氧氟沙星方案治疗的设为研究组(n=40);对比两组肺结核患者的治疗总有效率、不良反应(失眠、胃部不适、头晕、皮肤瘙痒)总发生率、生活质量评分(精神健康、生理机能以及社会功能)结果.结果:研究组肺

Abstract

Objective To explore the clinical effect of levofloxacin + anti-tuberculosis program in patients with pulmonary tuberculosis.Methods: 80 cases of pulmonary tuberculosis patients in our hospital from February 2020 to May 2022 were selected as research objects.Random number table method was used as the basis of treatment research grouping, and all pulmonary tuberculosis patients were divided into different groups.The control group (n=40) selected conventional anti-tuberculosis regimen.Based on the conventional regimen of the reference group, levofloxacin regimen was selected as the study group (n=40).The total effective rate, the total incidence of adverse reactions (insomnia, stomach upset, dizziness, pruritus), and quality of life score (mental health, physiological function, and social function) were compared between the two groups.Results:The total effective rate, the total incidence of adverse reactions (insomnia, stomach upset, dizziness, pruritus) and the scores of various indexes of quality of life of tuberculosis patients in the study group were compared with those in the reference group, and the results were significantly different (P<0.05).Conclusion: During the treatment of patients with pulmonary tuberculosis, the conventional anti-tuberculosis program can not be used to obtain obvious therapeutic effect. On this basis, combined with levofloxacin drug treatment, for the efficacy, safety and significant improvement of quality of life, can effectively promote.

关键词

左氧氟沙星/抗结核方案/肺结核/治疗总有效率/不良反应/生活质量评分

Key words

Levofloxacin/Anti-tuberculosis programme/Tuberculosis/Total effective rate of treatment/Adverse reaction/Quality of life score

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出版年

2023
健康大视野·医学分册
中国保健协会

健康大视野·医学分册

ISSN:1005-0019
参考文献量12
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