Objective To understand the needs of the permanent residents in Penglai area for health knowledge and health activities, and provide reference basis for future health education services.Methods: The sample was selected by random sampling method, and the self-designed questionnaire was used to conduct online questionnaire survey.Results: Among the 302 investigated, the oldest is 66 years old, the youngest is 20 years old, and the average age is (40.58 ± 18.17) years old; There was a statistical difference in the demand for various health knowledge between the gender groups (P<0.05), but there was no statistical difference in age, occupation, education level and residence (P>0.05); For the comparison of demand for health education forms, the difference between occupational groups was statistically significant (P<0.05), while the difference between age, sex, education level and residence was not statistically significant (P>0.05).Conclusion: Health education activities should be provided in a targeted manner to improve the reserve and ability of health-related knowledge, thus promoting healthy behavior and health status.