Objective To investigate the effects of lenalidomide treatment on clinical efficacy and β 2-microglobulin (β2-MG) and M protein (MP) levels in patients with multiple myeloma.Methods: A total of 40 patients with multiple myeloma admitted to Jinxiang County People''s Hospital from January 2018 to December 2021 were selected and divided into observation group and control group according to random number table method, with 20 patients in each group.The control group was given bortezomib and dexamethasone treatment, and the observation group was given lenalidomide treatment on the basis of the control group.The clinical efficacy, levels of β 2-Mg and MP were compared between the two groups.Results: Compared with the control group, the total remission rate (ORR) in observation group was higher (P＜0.05).The levels of β 2-Mg and MP in both groups were decreased after treatment (P＜0.05), and the levels of β 2-Mg and MP in observation group were lower than those in control group (P＜0.05). Conclusion: Lenalidomide has a good effect on patients with multiple myeloma, which can reduce the levels of β 2-Mg and MP.
关键词
多发性骨髓瘤/来那度胺/β2-微球蛋白/M蛋白
Key words
multiple myeloma/Lenalidomide/β 2-microglobulin/M protein
万方数据