Objective To analyze the application of plasma coagulation factors and platelet parameters in the diagnosis of severe cirrhosis.Methods: A total of 37 patients with severe cirrhosis who were treated in our hospital from January 2018 to July 2022 were selected as the observation group, and 41 healthy people who received physical examination during the same period were selected as the control group.The plasma coagulation factor and platelet parameters were detected in both groups, and the changes of plasma coagulation factor and platelet parameters were compared and analyzed between the two groups.Results: The plasma levels of APTT, TT and PT in the observation group were significantly higher than those in the control group (P ＜ 0.05), and the level of FIB was lower than that in the control group (P ＜ 0.05).The levels of coagulation factors ⅱ , ⅴ , ⅶ , ⅸ , ⅹ in the observation group were lower than those in the control group (P ＜ 0.05), and the level of ⅷ was higher than that in the control group (P ＜ 0.05).In terms of platelet parameters, the levels of PLT and PCT in the observation group were lower than those in the control group (P ＜ 0.05), and the levels of PDW and MPV in the observation group were higher than those in the control group (P ＜ 0.05).Conclusion: Compared with healthy people, patients with severe cirrhosis have significant changes in plasma coagulation factors and platelet parameters, which can be used as a basis for clinical diagnosis of severe cirrhosis.
关键词
重症肝硬化/血浆凝血因子/血小板参数/诊断价值
Key words
Severe liver cirrhosis/Plasma coagulation factor/Platelet parameters/Diagnostic value
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