摘要
目的:分析卵圆孔未闭(PFO)并发不明原因脑卒中(CS)、偏头痛患者接受介入封堵治疗的效果.方法:从2020年2月-2021年2月期间院内收治的卵圆孔未闭并发不明原因脑卒中、偏头痛患者内随机选择50例,对其实施增强经胸超声心动图(cTTE)、经颅多普勒超声发泡实验(cTCD)明确PFO结构大小,选择大小适宜的封堵器,对偏头痛患者治疗前实施头痛影响测定-6(HIT-6)评分,随后在术后1、3、6月复查cTTE、cTCD掌握疗效,详细记录随访症状,对偏头痛患者实施HIT-6评分,分析相关内容.结果:50例患者
Abstract
Objective To analyze the effect of interventional occlusion therapy in patients with patent foramen ovale (PFO) complicated with unexplained stroke (CS stroke) and migraine. Methods: 50 patients with unexplained stroke and migraine from February 2020 to February 2021, Implement enhanced transthoracic echocardiography (cTTE), transcranial Doppler ultrasound foaming experiment (cTCD) to determine the size of PFO structure, Select an occluder of the appropriate size, Implement headache impact test-6 (HIT-6) score before treatment, Subsequently, the efficacy of cTTE, cTCD in 1,3 and 6, Detailed recording of the follow-up symptoms, HIT-6 score in patients with migraine, Analyze the relevant content. Results: All 50 patients successfully completed PFO occlusion, no complications and symptoms improved. HIT-6 (67.54±3.54), HIT-6 (56.98±2.55), HIT-6 (69.65±3.17) at 3 months, and HIT-6 (44.27±3.45) at 6 months after surgery, with P ＜0.05. 50 preoperative cTCD detected 5,11 and 34.1 month postoperative review found 24 cases of right to left shunt, the residual shunt rate was 48％, 22 cases, 2 cases, 1 case, 3 months postoperative review found 8 cases of right to left shunt, the residual shunt rate was 16％, all grade. Four cases of right to left shunt was reviewed 6 months after surgery, with a residual shunt rate of 8％, all grade. Conclusion: PFO with unexplained stroke and migraine receive interventional occlusion therapy, which can significantly improve right to left shunt, relieve the symptoms of migraine patients, and prevent disease recurrence and new lesions with long-term follow-up results.
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