Objective To investigate the efficacy of lenalidomide plus R-CHOP regimen in diffuse large B cell lymphoma. Methods:The patients with 40 diffuse large B cell lymphoma (ABC subtype) admitted to our hospital from January 2018 to January 2020 were selected as the experimental group and treated with lenalidomide combined with R-CHOP regimen.40 patients with diffuse large B cell lymphoma (ABC subtype) treated with R-CHOP regimen were selected as the control group. To compare the treatment effects between the two groups .Results:The VE GF level of experimental group was significantly lower than control group; the complete response rate was higher than control group, statistically significant (P ＜0.05).The incidence of adverse reactions in the experimental group was not significantly different from that in the control group (P＞ 0.05). Conclusion:Lenalidomide combined with R-CHOP regimen has a significant efficacy on diffuse large B-cell lymphoma, which can significantly reduce the VE GF level, improve the remission rate , and has a high safety profile.
关键词
来那度胺/R-CHOP/弥漫大B细胞淋巴瘤/缓解率
Key words
lenalidomide/R-CHOP/diffuse large B cell lymphoma/remission rate
万方数据