目的:探究前列腺周围脂肪面积(Periprostatic fat area,PFA)与前列腺癌骨转移(Bone metastasis in prostate cancer,BM)具有相关性.方法:回顾性收集2019年1月至2021年12月120名前列腺患者,其中ECT/PET-CT已明确有骨转移的患者60例,无骨转移的60例,分别调取临床资料中各患者的年龄,PSA值,Gleason评分,并记录每个前列腺患者MRIT2序列影像中前列腺周围脂肪面积(PFA),前腹壁脂肪厚度(AAT)、后腹壁脂肪厚度(PAT)
Abstract
Objective To investigate the correlation between periprostatic fat area (PFA) and bone metastasis in prostate cancer (BM).Methods Retrospectively collected 120 prostate patients from January 2019 to December 2021, including 60 patients with definite bone metastasis by ECT/PETCT and 60 patients without bone metastasis, separately retrieved the age, PSA value, Gleason score of each patient in the clinical data, and recorded the periprostatic fat area (PFA) in MRI T2 sequence images of each prostate patient.The PFA, anterior abdominal wall fat thickness (AAT) and posterior abdominal wall fat thickness (PAT) indices were recorded for each prostate patient.Results Univariate regression analysis showed that periprostatic fat area (PFA) was correlated with prostate cancer bone metastasis (P＜0.01), whereas anterior abdominal wall fat thickness (AAT), posterior abdominal wall fat thickness (PAT) values, t-PSA and Gleason score were not correlated with prostate cancer (PCa) bone metastasis (P values 0.54, 0.06, 0.68, respectively).0.53).Conclusion There was a significant correlation between periprostatic fat area and bone metastases from prostate cancer.
关键词
前列腺癌/骨转移/前列腺周围脂肪/相关性
Key words
Bone metastasis of prostate cancer/peripheral prostatic fat/prediction
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