摘要
目的:临床案例回顾分析对比了解头孢菌素类药物用药不良反应及其预防、应对策略.方法:选取60例头孢菌素类药物用药患者进行回顾分析,对照组常规用药管理后根据其用药相关效果重新调整用药管理与处理方案后对观察组患者予以实施,对比两组患者用药情况.结果:接受常规用药管理的对照组患者中神经系统不良反应发生率23.33％(7/30),接受改善后用药管理的观察组患者神经系统不良反应发生率10.00％(3/30);接受常规用药管理的对照组患者消化系统不良反应发生率16.67％(5/30),接受改善后用药管理的观察组患者消化
Abstract
Objective Retrospective analysis of clinical cases to understand adverse drug reactions of cephalosporins and their prevention and coping strategies.Methods Sixty patients with cephalosporins were selected for retrospective analysis.After routine medication management in the control group, medication management and treatment plans were readjustedaccording to the medication related effects in the observation group, and drug use in the two groups was compared.Results The incidence of nervous system adverse reactions was 23.33％ (7/30) in the control group receiving conventional medication management, and 10.00％ (3/30) in the observation group receiving improved medication management.The incidence of adverse reactions of digestive system was 16.67％ (5/30) in the control group receiving conventional medication management, and 10.00％ (3/30) in the observation group receiving improved medication management.The incidence of respiratory adverse reactions was 3.33％ (1/30) in the control group receiving conventional medication management, and 3.33％ (1/30) in the observation group receiving improved medication management.The incidence of anaphylaxis was 6.67％ (2/30) in the control group receiving conventional medication management and 6.67％ (2/30) in the observation group receiving improved medication management.Conclusion Nephrotoxicity, digestive system, circulatory system, central nervous system, urinary system and allergic reaction are the main manifestations of adverse drug reactions of cephalosporins.It is necessary to pay attention to the dosage and compatibility of patients, and timely detect the liver and kidney function of patients for prevention and response.
万方数据